In the past decade, laboratories using LTS pipettes (Rainin LiteTouch System*) faced a single-supplier reality. While Rainin's revolutionary ergonomic design transformed pipetting comfort, the proprietary nature of LTS tips meant limited options and premium pricing. Today, Oxford Lab Products introduces an upgraded alternative with their new LTS-compatible tips that deliver exceptional performance at a fraction of the cost, backed by rigorous testing and innovative manufacturing techniques.
Product | SKU | Max Volume (uL): | Sterile | Low Retention | Filter | Racked | Reload Stack |
Oxford LTR 1000 uL Pipette Filter Tips | LTR-1000-SLF-N | 1000 | ✅ | ✅ | ✅ | ✅ | ❌ |
Oxford LTR 1000 uL Reload Pipette Tips | LTR-1000-LR-N | 1000 | ❌ | ✅ | ❌ | ❌ | ✅ |
Oxford LTR 1000 uL Pipette Tips | LTR-1000-SL-N | 1000 | ✅ | ✅ | ❌ | ✅ | ❌ |
Oxford LTR 200 uL Pipette Filter Tips | LTR-200-SLF-N | 200 | ✅ | ✅ | ✅ | ✅ | ❌ |
Oxford LTR 200 uL Reload Pipette Tips | LTR-200-LR-N | 200 | ❌ | ✅ | ❌ | ❌ | ✅ |
Oxford LTR 200 uL Pipette Tips | LTR-200-SL-N | 200 | ✅ | ✅ | ❌ | ✅ | ❌ |
Oxford LTR 20 uL Pipette Filter Tips | LTR-20-SLF-N | 20 | ✅ | ✅ | ✅ | ✅ | ❌ |
Oxford LTR 20 uL Reload Pipette Tips | LTR-20-LR-N | 20 | ❌ | ✅ | ❌ | ❌ | ✅ |
Oxford LTR 20 uL Pipette Tips | LTR-20-SL-N | 20 | ✅ | ✅ | ❌ | ✅ | ❌ |
For laboratories considering the switch to LTS-compatible tips, having the right pipette is equally important. The Accupet L pipette series offer full LTS compatibility while delivering the precision and ergonomic benefits that make Oxford's tips shine. When paired together, this combination maximizes both cost savings and performance.
The LTS Revolution - From Monopoly to Market Competition
The Rainin LiteTouch System fundamentally reimagined pipette tip design back in the 1970s. By replacing the traditional conical shaft with a cylindrical design that featured a thin sealing ring, LTS pipettes reduced tip attachment and tip ejection force by up to 85%[1]. This innovation significantly decreased the risk of repetitive strain injuries (RSI) - a critical concern for laboratory professionals performing thousands of pipetting operations daily.
However, this ergonomic breakthrough came at an expensive additional cost as laboratories were locked into a single supplier ecosystem. Nowadays, there are many emerging alternatives that challenged the past status quo with products offering the same benefits at decreased pricing. Among these alternatives, Oxford Lab Products emerges as the most compelling option, combining Swiss precision manufacturing with aggressive pricing that challenges the status quo.
Diamond-Finished Precision Meets Hydrophobic Science
Oxford's LTS tips aren't simply generic alternatives - they represent a sophisticated approach to pipette tip engineering. The manufacturing process begins with diamond-finished molds, creating an ultra-smooth interior surface that minimizes sample retention[2]. This precision tooling, typically reserved for premium medical devices, ensures consistent performance across millions of tips.
Their innovation also lies in Oxford's proprietary hydrophobic polymer formulation. Unlike competitors who apply silicon additives or surface coatings, Oxford integrates hydrophobic properties directly into the medical-grade polypropylene resin[3]. This approach eliminates the risk of leaching while achieving water contact angles that rival specialized low-retention tips.
Head-to-Head Performance in DNA Retention Study Results
Their comprehensive DNA retention study shows performance differences among leading LTS tip manufacturers[4]. Using Invitrogen's Qubit™ 1X dsDNA HS Assay Kit for ultra-sensitive detection, they have tested tips from Oxford and other manufacturers across multiple DNA concentrations.
Key Findings:
- Oxford LTR Tips: 0.0043% DNA loss at high concentration, zero detectable loss at lower concentrations
- Competitor T1: 0.0045% loss initially, lowering to 0.00144% at medium concentrations
- Competitor E1: 0.0058% to 0.01055% loss range, showing 2.4x higher retention than Oxford
- Competitor S: Highest retention at 0.0232% to 0.0257%, representing 5.4x more loss than Oxford
These results demonstrate Oxford's low retention technology matches or exceeds premium alternatives. For laboratories handling precious samples or performing sensitive molecular biology applications, this performance differential translates directly to improved experimental outcomes.
Built for Real-World Laboratory Conditions
Laboratory pipette tips face exposure to aggressive chemicals daily. Oxford's comprehensive chemical resistance testing reveals exceptional durability across common laboratory reagents[6]:
Excellent Resistance (Grade A) at Both 70°F and 120°F:
- Organic solvents: Acetone, Ethyl Alcohol (95% and 50%), Methyl Alcohol
- Acids: Acetic Acid (Glacial and 5%), Hydrochloric Acid (Concentrated and 10%), Hydrofluoric Acid (40%)
- Bases: Sodium Hydroxide Solutions (1%, 10%, and 60%)
- Oxidizers: Hydrogen Peroxide Solutions (3% and 28%)
This broad chemical compatibility ensures reliable performance across diverse applications from routine molecular biology to specialized chemical synthesis protocols.
Low Retention Performance with Challenging Solutions
Traditional low retention testing often uses pure water that is hardly representative of real laboratory conditions. Oxford's innovative testing protocol employs sodium laureth sulfate and Tween 80 solutions to simulate challenging, low surface tension liquids common in molecular biology workflows[7].
Results with Sodium Laureth Sulfate Solution:
- Oxford LTR: 0.0543 absorbance units retained
- Competitor Range: 0.0706 to 0.2086 absorbance units
- Performance Advantage: Up to 74% less retention than leading competitors
Results with Tween 80 Solution:
- Oxford LTR: 0.0473 absorbance units retained
- Competitor Range: 0.0523 to 0.1371 absorbance units
- Performance Advantage: Up to 65% less retention
These results prove Oxford tips maintain their low retention properties even with surfactant-containing solutions that typically increase sample adhesion.
Manufacturing Excellence: ISO Standards Meet Swiss Precision
Oxford Lab Products brings pharmaceutical-grade manufacturing standards to pipette tip production[2]:
Clean Room Environment: Class 100,000 certified facility with fully automated, touch-free processes
Quality Certifications: ISO 13485:2016 & ISO 9001:2015 compliance
Contamination Control: Certified free of DNase, RNase, ATP, PCR inhibitors, endotoxins and pyrogens
Material Safety: BPA-free, phthalate-free, cytotoxin-free, USP Class VI certified polymers
Sterilization: Gamma irradiation achieving SAL 10⁻⁶ for filtered tips
This commitment to quality ensures batch-to-batch consistency which is a critical factor for reproducible experimental results.
How Oxford Compares in the Competitive Landscape
With the LTS-compatible tips[5] market now including several major players, manufacturers offer laboratories diverse technological innovations - from advanced polymer formulations that reduce insertion forces to molecular-level surface refinements achieving ultra-low retention without additives.
Some manufacturers focus on regulatory certifications and medical device registrations, while others emphasize universal compatibility across pipette brands or specialized automation features. Premium offerings include RFID tracking capabilities and proprietary sealing technologies, though these often come at significant cost.
Based on our comprehensive feature analysis, Oxford LTR tips offer several capabilities rare in the current landscape[2]. As an official distributor of Oxford Lab Products, we're proud to offer tips that combine:
- True hydrophobic polymer integration - not a surface coating
- Diamond-finished mold technology for ultra-smooth surfaces
- Shock-absorbing ejection design reducing hand strain
- Graduated markings on all tip sizes for volume verification
- Thin-wall technology maximizing sample recovery
- Universal rack compatibility with standard SBS footprint
Application-Specific Benefits
Whether you're using an Accupet L or other LTS-compatible pipettes, Oxford tips deliver consistent results across these key applications:
For Molecular Biology:
- Zero detectable DNA loss at working concentrations[4]
- Compatible with restriction enzymes and sensitive reagents
- Certified nuclease-free for PCR and sequencing applications
For Cell Cultures:
- Low protein binding for accurate cell counting
- Sterile options prevent contamination
- Chemical resistance to common media components[6]
For Analytical Chemistry:
- Excellent organic solvent compatibility
- Consistent dimensions for reproducible liquid handling
- Low extractables verified by USP Class VI testing
Sustainability and Environmental Impact
Recent industry trends show increasing demand for sustainable laboratory consumables, with bio-based plastics and reduced packaging becoming standard requirements[9]. While maintaining performance, Oxford also addresses growing environmental concerns[2] with the following features:
- Recyclable polypropylene construction
- Efficient manufacturing minimizing energy consumption
- No silicon additives - eliminating environmental persistence concerns
Performance and Quality Without the Harsh Price Tag
For laboratories seeking to optimize budgets without compromising results, Oxford LTR tips represent a compelling solution. With a performance matching or exceeding premium alternatives[4,7] and cost savings of 50-70% versus other suppliers[5] creates unprecedented value in the liquid handling market with a combination of Swiss precision manufacturing and innovative polymer chemistry.
For the complete liquid handling solution, consider pairing Oxford LTR tips with Accupet L pipettes - a combination that delivers laboratory-grade precision at competitive pricing.
About Oxford Lab Products
Oxford Lab Products specializes in high-quality laboratory consumables and liquid handling solutions. With ISO 13485:2016 and ISO 9001:2015 certifications, the company serves research institutions, pharmaceutical companies and clinical laboratories worldwide.
Their commitment to innovation and value has established Oxford as a trusted partner for laboratories seeking to advance science without breaking budgets.
For more information about Oxford LTR pipette tips or to request samples, visit www.oxfordlp.com.
* Rainin is a registered trademark of Mettler-Toledo International Inc.
References
- "Rainin LiteTouch System (LTS)" Mettler Toledo
- "LTS Pipette Tips Product Brochure" Oxford Lab Products
- "LTS Pipette Tips Technical Data Sheet" Oxford Lab Products
- "Evaluating Low Retention Tips for DNA Handling" Oxford Lab Products
- "LTS Compatible Pipette Tips" Pipette.com
- "Chemical Resistance Chart" Oxford Lab Products
- "Low Retention Tips Comparison Study" Oxford Lab Products
- "Oxford LTR Pipette Tips LTS Compatible" Pipette.com
- "Science-friendly, planet-friendly: Pipette tips go green" Science.org